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Myelination of brain nerve axon membranes is accomplished by


A) oligodendrocytes.
B) microglia.
C) astrocytes.
D) neurocytes.
E) Schwann cells.

F) All of the above
G) A) and B)

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_______ are charged particles formed when an electrolyte dissolves in water.


A) Ions
B) Solvents
C) Transmitters
D) Electrons
E) Solutes

F) None of the above
G) C) and E)

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Which of the following was suggested as an advantage associated with myelination?


A) Myelin changes the height of the action potential.
B) Myelin increases the energy requirements of the nerve cell.
C) Myelin slows down conduction speed.
D) Myelin reduces the threshold for induction of an action potential.
E) Myelin speeds up axon conduction speed.

F) C) and D)
G) A) and E)

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2- As it conducts along the axon membrane toward the terminal buttons, a subthreshold depolarization ________ in size.

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The nucleus of the nerve cell is located within the


A) soma.
B) axon.
C) axon terminals.
D) dendrites.
E) mitochondria.

F) C) and E)
G) B) and E)

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The function of a _______ in a giant squid physiology experiment is to _______.


A) microelectrode; inject potassium ions into the axon
B) voltmeter; stimulate the interior of the axon
C) microelectrode; compare the electric charge of the interior with that of the exterior
D) voltmeter; compare the electric charge of the interior with that of the exterior
E) microelectrode; dampen the electric charge within the axon

F) B) and C)
G) B) and D)

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Explain why the termination step of the neural communication process is a key target for therapeutic drugs.

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Autoreceptors are sensitive to the trans...

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2-________ receptors involve the direct opening of an ion channel, whereas metabotropic receptors involve the action of second messenger molecules inside the postsynaptic cell.

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The interior of a neuron at rest


A) has the same ionic concentrations as the outside.
B) is at the same voltage potential as the outside.
C) has a higher sodium concentration than outside.
D) is negatively charged relative to the outside.
E) has a lower potassium concentration than outside.

F) A) and C)
G) A) and B)

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As a consequence of the activity of the sodium-potassium transporters,


A) extracellular sodium concentrations are kept low.
B) intracellular sodium concentrations are kept very high.
C) extracellular potassium concentrations are kept very high.
D) intracellular sodium concentrations are kept low.
E) very little energy is required to maintain ionic differences across the membrane.

F) C) and E)
G) C) and D)

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Movement of _______ ions _______ the axon would be induced by the force of diffusion.


A) chloride; out of
B) sodium; into
C) potassium; into
D) organic; into
E) sodium; out of

F) B) and D)
G) A) and B)

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_______ neurons function to contract muscles.


A) Sensory
B) Motor
C) Inter-
D) Relay
E) Local

F) B) and C)
G) C) and E)

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Motor neurons control the activity of the ________.

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Which of the following is correct regarding axoplasmic transport?


A) Dendrograde transport involves moving substances from the dendrites to the soma.
B) Retrograde transport involves moving substances from the soma to the axon terminals.
C) The kinesin molecule is involved in anterograde transport.
D) Retrograde transport is twice as fast as anterograde transport.
E) The dynein molecule is involved in anterograde transport.

F) A) and B)
G) B) and D)

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With regard to release of neurotransmitter in the brain, "kiss and run" refers to the situation in which the vesicle


A) releases most of its contents into the cleft and the vesicle remains attached to the presynaptic membrane.
B) closes before releasing any molecules and then moves to the cell interior.
C) remains open until the next action potential.
D) releases most of its contents into the cleft after which the vesicle breaks away from the presynaptic membrane and is refilled.
E) merges completely with the presynaptic membrane.

F) D) and E)
G) A) and C)

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________ are bead-like structures that extract energy from nutrients.

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The primary symptom shown by Kathryn D. was


A) severe nausea.
B) inability to sleep.
C) muscle weakness.
D) distortions of memory.
E) difficulty in recognizing facial displays of emotion.

F) A) and B)
G) B) and E)

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Loss of dendritic branches on _______ would be expected to impair the ability to sense temperature and touch.


A) bipolar neurons
B) multipolar neurons
C) unipolar neurons
D) apolar neurons
E) motor neurons

F) B) and E)
G) None of the above

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Which of the following represents a correct match between a neuronal organelle and its function?


A) mitochondria; extraction of energy
B) Golgi apparatus; extraction of energy
C) endoplasmic reticulum; breakdown of proteins
D) microtubules; transport of chemicals through the cell membrane
E) mitochondria; formation of vesicles

F) A) and C)
G) None of the above

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Presynaptic facilitation is associated with _______ synapses and involves a(n) _______ in the amount of transmitter released per action potential.


A) axodendritic; decrease
B) axosomatic; increase
C) gap junction; decrease
D) axoaxonic; increase
E) gap junction; increase

F) All of the above
G) A) and E)

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