Question 1

Which of the following is not a drug group used to treat fungal infections?

Accepted Answer

A)  Quinolones
B)  Macrolide polyenes
C)  Echinocandins
D)  Synthetic azoles
E)  AllylaminesF) C) and E)
G) D) and E)

Question 2

Aminoglycosides ________.

Accepted Answer

A)  interfere with elongation of peptidoglycan
B)  block folic acid synthesis
C)  attach to the 30S ribosomal subunit and disrupt protein synthesis
D)  damage cell membranes
E)  block peptidases that cross-link glycan moleculesF) All of the above
G) None of the above

Question 3

Which of the following is not a mode of action of antiviral drugs?

Accepted Answer

A)  Block penetration
B)  Block transcription and translation
C)  Inhibit DNA synthesis
D)  Block maturation
E)  Bond to ergosterol in the cell membraneF) None of the above
G) C) and D)

Question 4

When a patient's immune system reacts adversely to a drug,this serious side effect is called a superinfection.

Accepted Answer

A) True 
 B)False

Question 5

There are fewer antifungal,antiprotozoan,and antihelminth drugs compared to antibacterial drugs because fungi,protozoa,and helminths ________.

Accepted Answer

A)  do not cause many human infections
B)  are not affected by antimicrobials
C)  are so similar to human cells that drug selective toxicity is difficult
D)  are parasites found inside human cells
E)  have cells with fewer target sites compared to bacteriaF) D) and E)
G) C) and D)

Question 6

Microbial resistance resulting from mutation occurs because ________.

Accepted Answer

A)  bacterial genomes undergo mutation rapidly
B)  bacterial genomes undergo mutation often
C)  short generation times accumulate mutations in populations
D)  mutations are passed between organisms
E)  All of the choices are correct.F) B) and D)
G) B) and C)

Question 7

Each of the following result in drug resistance except ________.

Accepted Answer

A)  drug pumped out of the cell
B)  drug used as a nutrient by the cell
C)  drug binding site altered
D)  drug inactivated
E)  drug blocked from entering cellF) A) and B)
G) A) and C)

Question 8

Drugs that are hepatotoxic cause damage to a patient's kidneys.

Accepted Answer

A) True 
 B)False

Question 9

An RN in a medical intensive care unit is leading a research study regarding administration of probiotics to critically ill patients receiving antibiotic therapy. She provides education about normal flora and probiotics as part of the consent process to patients and families.
-Which of the following is an example of a probiotic?

Accepted Answer

A)  Penicillin
B)  Micafungin
C)  Yogurt
D)  FructansE) A) and D)
F) C) and D)

Question 10

The MIC is the smallest concentration of an antimicrobial required to inhibit the growth of the microbe.

Accepted Answer

A) True 
 B)False

Question 11

Which of these drugs has the most narrow spectrum?

Accepted Answer

A)  Tetracycline
B)  Isoniazid
C)  Erythromycin
D)  Aminoglycosides
E)  CephalosporinsF) B) and E)
G) B) and D)

Question 12

Which of the following is not true of polymyxins?

Accepted Answer

A)  Disrupt the cell membrane
B)  Have a narrow spectrum
C)  Toxic to kidneys
D)  Target peptidoglycan
E)  Can treat severe urinary tract infectionsF) A) and E)
G) B) and C)

Question 13

Ampicillin,amoxicillin,mezlocillin,and penicillin G all ________.

Accepted Answer

A)  target the cell wall
B)  have resistance to the action of penicillinase
C)  are semisynthetic
D)  have an expanded spectrum of activity
E)  All of the choices are correct.F) A) and B)
G) None of the above

Question 14

Each of the following contributes to emerging drug resistance except ________.

Accepted Answer

A)  overuse of antibiotics
B)  improper use of antibiotics
C)  multiple drug therapy
D)  ingestion of antibiotics with animal feed
E)  addition of antibiotics to common household productsF) None of the above
G) C) and E)

Question 15

Which of the following statements does not accurately reflect the origins of antimicrobial drugs?

Accepted Answer

A)  All antimicrobial drugs are synthesized by medicinal chemists in a laboratory environment.
B)  Bacteria and fungi are natural producers of antimicrobial drugs; the molecules are synthesized to maintain competition for nutrients and space to a minimum.
C)  Scientists have learned how to modify antimicrobial molecules naturally produced by organisms to enhance their efficacy and range.
D)  Some antimicrobial agents are synthesized wholly in the laboratory.E) A) and C)
F) None of the above

Question 16

Antiviral drugs that target reverse transcriptase would be used to treat ________.

Accepted Answer

A)  influenza A virus
B)  HIV
C)  herpes zoster virus
D)  respiratory syncytial virus
E)  hepatitis C virusF) A) and E)
G) B) and D)

Question 17

The use of a drug to prevent a person at risk of an imminent infection is called ________.

Accepted Answer

A)  competitive inhibition
B)  synergism
C)  prebiotics
D)  prophylaxis
E)  lantibioticsF) C) and D)
G) A) and E)

Question 18

The antifungal drug that can be injected to treat serious systemic fungal infections,like histoplasmosis,is ________.

Accepted Answer

A)  nystatin
B)  griseofulvin
C)  amphotericin B
D)  sulfa drugs
E)  metronidazoleF) B) and D)
G) D) and E)

Question 19

Ketoconazole,fluconazole,clotrimazole,miconazole are broad-spectrum azoles used to treat ________ infections.

Accepted Answer

A)  bacterial
B)  fungal
C)  protozoan
D)  helminthic
E)  viralF) A) and B)
G) C) and D)

Question 20

Which of the following antibacterial drug groups does not target protein synthesis?

Accepted Answer

A)  Clindamycin
B)  Erythromycin
C)  Aminoglycosides
D)  Sulfonamides
E)  TetracyclineF) B) and E)
G) A) and E)

Exam 10: Antimicrobial Treatment

The MIC is the smallest concentration of an antimicrobial required to inhibit the growth of the microbe.

Correct Answer
verified

Each of the following contributes to emerging drug resistance except ________.

Correct Answer
verified

Which of the following antibacterial drug groups does not target protein synthesis?

Correct Answer
verified

When a patient's immune system reacts adversely to a drug,this serious side effect is called a superinfection.

Correct Answer
verified

Aminoglycosides ________.

Correct Answer
verified

Each of the following result in drug resistance except ________.

Correct Answer
verified

Microbial resistance resulting from mutation occurs because ________.

Correct Answer
verified

Ketoconazole,fluconazole,clotrimazole,miconazole are broad-spectrum azoles used to treat ________ infections.

Correct Answer
verified

Drugs that are hepatotoxic cause damage to a patient's kidneys.

Correct Answer
verified

Which of the following is not true of polymyxins?

Correct Answer
verified

Which of these drugs has the most narrow spectrum?

Correct Answer
verified

Correct Answer
verified

Ampicillin,amoxicillin,mezlocillin,and penicillin G all ________.

Correct Answer
verified

Which of the following is not a mode of action of antiviral drugs?

Correct Answer
verified

Antiviral drugs that target reverse transcriptase would be used to treat ________.

Correct Answer
verified

Which of the following is not a drug group used to treat fungal infections?

Correct Answer
verified

The antifungal drug that can be injected to treat serious systemic fungal infections,like histoplasmosis,is ________.

Correct Answer
verified

The use of a drug to prevent a person at risk of an imminent infection is called ________.

Correct Answer
verified

Which of the following statements does not accurately reflect the origins of antimicrobial drugs?

Correct Answer
verified

There are fewer antifungal,antiprotozoan,and antihelminth drugs compared to antibacterial drugs because fungi,protozoa,and helminths ________.

Correct Answer
verified

Exam 10: Antimicrobial Treatment

The MIC is the smallest concentration of an antimicrobial required to inhibit the growth of the microbe.

Correct AnswerverifiedShow Answer

Each of the following contributes to emerging drug resistance except ________.

Correct AnswerverifiedShow Answer

Which of the following antibacterial drug groups does not target protein synthesis?

Correct AnswerverifiedShow Answer

When a patient's immune system reacts adversely to a drug,this serious side effect is called a superinfection.

Correct AnswerverifiedShow Answer

Aminoglycosides ________.

Correct AnswerverifiedShow Answer

Each of the following result in drug resistance except ________.

Correct AnswerverifiedShow Answer

Microbial resistance resulting from mutation occurs because ________.

Correct AnswerverifiedShow Answer

Ketoconazole,fluconazole,clotrimazole,miconazole are broad-spectrum azoles used to treat ________ infections.

Correct AnswerverifiedShow Answer

Drugs that are hepatotoxic cause damage to a patient's kidneys.

Correct AnswerverifiedShow Answer

Which of the following is not true of polymyxins?

Correct AnswerverifiedShow Answer

Which of these drugs has the most narrow spectrum?

Correct AnswerverifiedShow Answer

Correct AnswerverifiedShow Answer

Ampicillin,amoxicillin,mezlocillin,and penicillin G all ________.

Correct AnswerverifiedShow Answer

Which of the following is not a mode of action of antiviral drugs?

Correct AnswerverifiedShow Answer

Antiviral drugs that target reverse transcriptase would be used to treat ________.

Correct AnswerverifiedShow Answer

Which of the following is not a drug group used to treat fungal infections?

Correct AnswerverifiedShow Answer

The antifungal drug that can be injected to treat serious systemic fungal infections,like histoplasmosis,is ________.

Correct AnswerverifiedShow Answer

The use of a drug to prevent a person at risk of an imminent infection is called ________.

Correct AnswerverifiedShow Answer

Which of the following statements does not accurately reflect the origins of antimicrobial drugs?

Correct AnswerverifiedShow Answer

There are fewer antifungal,antiprotozoan,and antihelminth drugs compared to antibacterial drugs because fungi,protozoa,and helminths ________.

Correct AnswerverifiedShow Answer

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