Question 1

Which compound would be the most useful to treat candidiasis?

Accepted Answer

A)  uracil
B)  thymine
C)  flucytosine
D)  guanine
E)  penicillinF) A) and D)
G) None of the above

Question 2

Which of the following does NOT affect eukaryotic cells?

Accepted Answer

A)  antiprotozoan drugs
B)  antihelminthic drugs
C)  antifungal drugs
D)  nucleotide analogs
E)  semisynthetic penicillinsF) D) and E)
G) B) and E)

Question 3

Which of the following antimicrobial agents is recommended for use against fungal infections?

Accepted Answer

A)  amphotericin B
B)  bacitracin
C)  cephalosporin
D)  penicillin
E)  polymyxinF) All of the above
G) B) and E)

Question 4

An official from an international health agency predicts that if all countries enacted legislation to only sell antibiotics with a prescription,then the rate of antibiotic resistant would "grind to a halt." Do you agree? Explain.

Accepted Answer

I agree with the official from the inter...

Question 5

Figure 20.1
 
-In Figure 20.1,why is tetracycline selectively toxic against bacteria?

Accepted Answer

A)  Eukaryotic cells will enzymatically destroy the drug.
B)  Eukaryotic cells will actively pump the drug out of their interiors.
C)  The drug affects peptidoglycan synthesis,and eukaryotic cells have no peptidoglycan.
D)  The drug binds to the 30S small ribosomal subunit - eukaryotes have a 40S small subunit.
E)  Eukaryotes lack a small ribosomal subunit,so the drug cannot negatively affect them.F) C) and E)
G) B) and D)

Question 6

Figure 20.4 
The structures of the influenza drug Tamiflu and sialic acid,the substrate for influenza virus's neuramidase,are shown in Figure 20.4.What is the method of action of Tamiflu?

Accepted Answer

A)  inhibits cell wall synthesis
B)  inhibits plasma membrane synthesis
C)  inhibits synthesis of neuramidase
D)  competitive inhibition
E)  prevents synthesis of virus spikesF) B) and E)
G) C) and D)

Question 7

In what way are semisynthetic penicillins and natural penicillins alike?

Accepted Answer

A)  Both are broad spectrum.
B)  Both are resistant to penicillinase.
C)  Both are resistant to stomach acids.
D)  Both are bactericidal.
E)  Both are based on β-lactam.F) All of the above
G) None of the above

Question 8

Mebendazole is used to treat cestode infections.It interferes with microtubule formation;therefore,it would NOT affect

Accepted Answer

A)  bacteria.
B)  fungi.
C)  helminths.
D)  human cells.
E)  protozoa.F) A) and C)
G) A) and B)

Question 9

Antimicrobial peptides (AMPs) frequently work by

Accepted Answer

A)  inhibiting protein synthesis.
B)  disrupting the plasma membrane.
C)  complementary base pairing with DNA.
D)  inhibiting cell-wall synthesis.
E)  hydrolyzing peptidoglycan.F) None of the above
G) A) and D)

Question 10

Penicillin was considered a "miracle drug" for all of the following reasons EXCEPT

Accepted Answer

A)  it was the first antibiotic.
B)  it does not affect eukaryotic cells.
C)  it inhibits gram-positive cell wall synthesis.
D)  it has selective toxicity.
E)  it kills bacteria.F) A) and E)
G) A) and C)

Question 11

Penicillin does not directly kill bacteria.Why,then,is it considered to be bacteriocidal?

Accepted Answer

Penicillin is considered bactericidal be...

Question 12

Figure 20.2
 
-The antibiotic chloramphenicol binds to the 50S subunit of the ribosome,as shown in Figure 20.2.The effect is to

Accepted Answer

A)  prevent mRNA-ribosome binding in eukaryotes.
B)  prevent peptide bond formation in prokaryotes.
C)  prevent polypeptide elongation in eukaryotes.
D)  prevent transcription in prokaryotes.
E)  prevent ribosome formation in bacteria.F) A) and C)
G) A) and D)

Question 13

Which of the following statements about drug resistance is FALSE?

Accepted Answer

A)  It may be carried on a plasmid.
B)  It may be transferred from one bacterium to another during conjugation.
C)  It may be due to enzymes that degrade some antibiotics.
D)  It is found only in gram-negative bacteria.
E)  It may be due to decreased uptake of a drug.F) B) and C)
G) D) and E)

Question 14

PABA serves as the competitive inhibitor in the action of sulfanilamides.

Accepted Answer

A) True 
 B)False

Question 15

From the data in Table 20.1,you can predict that the effect of the drug on a different microbe

Accepted Answer

A)  will be the same.
B)  will be weaker.
C)  will be stronger.
D)  can't be predicted from the information provided.E) A) and D)
F) A) and B)

Question 16

Due to its target,rifamycins such as rifampin can be effective over a broad spectrum.

Accepted Answer

A) True 
 B)False

Question 17

In the presence of penicillin,a cell dies because

Accepted Answer

A)  it lacks a cell wall.
B)  it plasmolyzes.
C)  it undergoes lysis.
D)  it lacks a cell membrane.
E)  its contents leak out.F) A) and B)
G) B) and D)

Question 18

Figure 20.1
 
-The antibiotic tetracycline binds to the 30S subunit of the ribosome,as shown by the dark black bar on the right portion of the diagram in Figure 20.1.The effect is to

Accepted Answer

A)  prevent attachment of DNA.
B)  prevent peptide bond formation.
C)  prevent transcription.
D)  stop the ribosome from moving along the mRNA.
E)  interfere with the attachment of the tRNA to mRNA-ribosome complex.F) All of the above
G) C) and D)

Question 19

Phage therapy has been used in the past as an effective,common antiviral treatment.

Accepted Answer

A) True 
 B)False

Question 20

Most of the available antimicrobial agents are effective against

Accepted Answer

A)  viruses.
B)  bacteria.
C)  fungi.
D)  protozoa.E) A) and C)
F) A) and B)

Exam 20: Antimicrobial Drugs

Antimicrobial peptides (AMPs) frequently work by

Correct AnswerverifiedShow Answer

Figure 20.2 -The antibiotic chloramphenicol binds to the 50S subunit of the ribosome,as shown in Figure 20.2.The effect is to

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Which of the following statements about drug resistance is FALSE?

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PABA serves as the competitive inhibitor in the action of sulfanilamides.

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Penicillin does not directly kill bacteria.Why,then,is it considered to be bacteriocidal?

Correct AnswerAnswered by ExamLex AIPenicillin is considered bactericidal be...View AnswerShow Answer

Figure 20.1 -The antibiotic tetracycline binds to the 30S subunit of the ribosome,as shown by the dark black bar on the right portion of the diagram in Figure 20.1.The effect is to

Correct AnswerverifiedShow Answer

Which of the following antimicrobial agents is recommended for use against fungal infections?

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Which of the following does NOT affect eukaryotic cells?

Correct AnswerverifiedShow Answer

Penicillin was considered a "miracle drug" for all of the following reasons EXCEPT

Correct AnswerverifiedShow Answer

From the data in Table 20.1,you can predict that the effect of the drug on a different microbe

Correct AnswerverifiedShow Answer

In the presence of penicillin,a cell dies because

Correct AnswerverifiedShow Answer

Figure 20.1 -In Figure 20.1,why is tetracycline selectively toxic against bacteria?

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Phage therapy has been used in the past as an effective,common antiviral treatment.

Correct AnswerverifiedShow Answer

An official from an international health agency predicts that if all countries enacted legislation to only sell antibiotics with a prescription,then the rate of antibiotic resistant would "grind to a halt." Do you agree? Explain.

Correct AnswerAnswered by ExamLex AII agree with the official from the inter...View AnswerShow Answer

Mebendazole is used to treat cestode infections.It interferes with microtubule formation;therefore,it would NOT affect

Correct AnswerverifiedShow Answer

Figure 20.4 The structures of the influenza drug Tamiflu and sialic acid,the substrate for influenza virus's neuramidase,are shown in Figure 20.4.What is the method of action of Tamiflu?

Correct AnswerverifiedShow Answer

Most of the available antimicrobial agents are effective against

Correct AnswerverifiedShow Answer

Due to its target,rifamycins such as rifampin can be effective over a broad spectrum.

Correct AnswerverifiedShow Answer

Which compound would be the most useful to treat candidiasis?

Correct AnswerverifiedShow Answer

In what way are semisynthetic penicillins and natural penicillins alike?

Correct AnswerverifiedShow Answer

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Penicillin is considered bactericidal be...
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I agree with the official from the inter...
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