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Select the correct statement about the nephrons.


A) Podocytes are the branching epithelial cells that line the tubules of the nephron.
B) The parietal layer of the glomerular capsule is simple squamous epithelium.
C) The glomerulus is correctly described as the proximal end of the proximal convoluted tubule.
D) Filtration slits are the pores that give fenestrated capillaries their name.

E) All of the above
F) None of the above

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The mechanism that establishes the medullary osmotic gradient depends most on the permeability properties of the ________.


A) collecting duct
B) glomerular filtration membrane
C) nephron loop
D) distal convoluted tubule

E) A) and C)
F) None of the above

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If blood pressure drops very low (MAP is below 80mmHg) renin enzyme will be secreted by granular cells.Which of the following is not likely to occur?


A) Blood plasma and extracellular fluids volume will increase
B) Glomerular filtration rate (GFR) will decrease
C) Net filtration pressure (NFP) will decrease
D) Kidney perfusion will increase

E) B) and C)
F) A) and D)

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Which of the choices below is not a method by which the cells of the renal tubules can raise blood pH?


A) by producing new bicarbonate ions
B) by reabsorbing filtered bicarbonate ions
C) by secreting hydrogen ions into the filtrate
D) by secreting sodium ions

E) A) and B)
F) None of the above

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The presence of pus in the urine is a condition called ________.

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Aldosterone is a hormone that causes the renal tubules to reclaim sodium ions from the filtrate.

A) True
B) False

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An important characteristic of urine is its specific gravity or density,which is ________.


A) less than water
B) much higher than water
C) the same as water
D) slightly higher than water

E) B) and D)
F) All of the above

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D

Ellen,a 47-year-old woman who has suffered kidney disease for several years,has been diagnosed with proteinuria.Her legs and feet are so swollen that she has difficulty walking.Her hands and her left arm are also swollen.What is proteinuria,and could this condition be playing a role in her swollen limbs?

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Proteinuria is a condition in which the ...

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The relatively long half-life of lipid soluble hormones (steroid hormones) compared to water soluble hormones is due in part to the way that these hormones are passed into the filtrate from the glomerular capillaries.From the list below select the best explanation for why lipid soluble (steroid) hormones have a relatively long half-life.


A) The large size of the steroid hormones prevents them from passing through the filtration membrane.
B) Steroid hormones are absorbed by target cells before they can reach the kidneys.
C) The relatively small size of steroid hormones allows them to easily pass back into the peritubular capillaries if released into the filtrate.
D) Steroid hormones travel in the plasma on large transport proteins that cannon pass through the filtration membrane.

E) A) and B)
F) A) and D)

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The path urine takes after it is formed until it leaves the body is the urethra,urinary bladder,and finally the ureter.

A) True
B) False

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If the diameter of the efferent arterioles leading away from the glomerulus increases (vasodilation) which of the following is not likely to occur?


A) Urine output will decrease.
B) Net filtration pressure will decrease.
C) Systemic blood pressure will decrease.
D) Glomerular filtration rate will decrease.

E) B) and D)
F) All of the above

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Place the following in correct sequence from the formation of a drop of urine to its elimination from the body. 1.major calyx 2) minor calyx 3) nephron 4) urethra 5) ureter 6) collecting duct


A) 6,3,2,1,5,4
B) 3,6,2,1,5,4
C) 3,1,2,6,5,4
D) 2,1,3,6,5,4

E) B) and C)
F) A) and C)

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Angiotensin II is a substance made by the body to lower blood pressure during stress.

A) True
B) False

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False

If one says that the clearance value of glucose is zero,what does this mean?


A) Normally all the glucose is reabsorbed.
B) The clearance value of glucose is relatively high in a healthy adult.
C) The glucose molecule is too large to be filtered out of the blood.
D) Most of the glucose is filtered out of the blood and is not reabsorbed in the convoluted tubules.

E) C) and D)
F) A) and D)

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Which of the following acts as the trigger for the initiation of micturition (voiding) ?


A) the pressure of the fluid in the bladder
B) motor neurons
C) the stretching of the bladder wall
D) the sympathetic efferents

E) C) and D)
F) B) and C)

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The trigone is so named because of the shape of the urinary bladder.

A) True
B) False

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Explain how filtration works in the glomerular capillaries.

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The glomerular capillaries are fenestrated,allowing fairly large molecules to pass through.The substances must pass through the basement membrane,where they are further selected for size by the filtration slits of the podocytes.

The fluid in glomerular capsule is similar to plasma except that it does not contain a significant amount of ________.


A) electrolytes
B) hormones
C) glucose
D) plasma protein

E) A) and D)
F) None of the above

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Which of the choices below are the most important hormone regulators of electrolyte reabsorption and secretion?


A) angiotensin I and epinephrine
B) angiotensin I and atrial natriuretic peptide
C) angiotensin II and ADH
D) angiotensin II and aldosterone

E) B) and C)
F) A) and D)

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Which of the choices below is not a glomerular filtration rate control method?


A) electrolyte levels
B) hormonal regulation
C) renal autoregulation
D) neural regulation

E) A) and B)
F) A) and D)

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