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All of the following are iron- binding proteins found in humans EXCEPT


A) ferritin.
B) transferrin.
C) siderophorin.
D) hemoglobin.
E) lactoferrin.

F) B) and C)
G) B) and D)

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Which of the following is an effect of opsonization?


A) increased margination of phagocytes
B) cytolysis
C) inflammation
D) increased diapedesis of phagocytes
E) increased adherence of phagocytes to microorganisms

F) B) and D)
G) A) and B)

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Margination refers to


A) the chemotactic response of phagocytes.
B) the adherence of phagocytes to microorganisms.
C) dilation of blood vessels.
D) the movement of phagocytes through walls of blood vessels.
E) adherence of phagocytes to the lining of blood vessels.

F) A) and B)
G) A) and E)

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The swelling associated with inflammation decreases when the fluid


A) is transported into macrophages.
B) goes into lymph capillaries.
C) is lost as perspiration.
D) is excreted in urine.
E) returns to the blood.

F) A) and C)
G) B) and C)

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Which of the following statements about fixed macrophages is FALSE?


A) They gather at sites of infection.
B) They are found in certain tissues and organs.
C) They develop from neutrophils.
D) They are mature monocytes.
E) They are cells of the mononuclear phagocytic system.

F) A) and E)
G) A) and C)

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The antimicrobial effects of AMPs include all of the following EXCEPT


A) pore formation in bacterial membranes.
B) destruction of nucleic acids.
C) inhibition of cell wall synthesis.
D) lysis of bacterial cells.
E) inhibition of phagocytosis.

F) C) and D)
G) B) and E)

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An example of a TLR would be peptidoglycan found in the cell wall of gram- positive bacteria.

A) True
B) False

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Innate immunity includes all of the following EXCEPT


A) activation of complement.
B) phagocytosis.
C) inflammation.
D) production of interferon.
E) production of antibody.

F) None of the above
G) C) and D)

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Maturation of stem cells into mature blood cells occurs in the red bone marrow.

A) True
B) False

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Lysozyme and the antibiotic penicillin have similar mechanisms of action in that they both cause damage to the bacterial


A) DNA.
B) cell membrane.
C) ribosomes.
D) capsule.
E) cell wall.

F) B) and D)
G) All of the above

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Explain how each of the following avoids being killed by phagocytes. a. Streptococcus pneumoniae b. Mycobacterium tuberculosis c. Streptococcus pyogenes d. Shigella dysenteriae

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Answered by ExamLex AI

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a. Streptococcus pneumoniae avoids being...

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The complement protein cascade is the same for the classical pathway, alternative pathway, and lectin pathway beginning with the activation of


A) C1.
B) C2.
C) C3.
D) C5.
E) C6.

F) All of the above
G) A) and B)

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Each of the following is an effect of complement activation EXCEPT


A) interference with viral replication.
B) bacterial cell lysis.
C) opsonization.
D) increased blood vessel permeability.
E) increased phagocytic activity.

F) B) and E)
G) A) and C)

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Which of the following statements is TRUE?


A) Alpha interferon promotes phagocytosis.
B) Beta interferon attacks invading viruses.
C) Alpha interferon acts against specific viruses.
D) All three types of interferons have the same effect on the body.
E) Gamma interferon causes bactericidal activity by macrophages.

F) C) and E)
G) B) and C)

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All of the following are effects of histamine EXCEPT


A) isolation of an injurious agent.
B) repair of damaged tissue.
C) production of antibodies.
D) removal of an injurious agent.
E) destruction of an injurious agent.

F) C) and D)
G) All of the above

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Several inherited deficiencies in the complement system occur in humans. Which of the following would be the MOST severe?


A) deficiency of C3
B) deficiency of C5
C) deficiency of C6
D) deficiency of C7
E) deficiency of C8

F) A) and B)
G) A) and C)

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Phagocytes utilize all of the following to optimize interaction with microorganisms EXCEPT


A) chemotaxis.
B) complement.
C) opsonization.
D) trapping a bacterium against a rough surface.
E) lysozyme.

F) A) and B)
G) A) and C)

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