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The largest of the viruses are similar in size to some small bacteria and are large enough to be seen with a light microscope.

A) True
B) False

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Which of the following is true of viruses in the extracellular phase?


A) They possess many different enzymes.
B) They can reproduce independently of living cells but only at a slow rate.
C) They behave as a macromolecular complex and are no more alive than are ribosomes.
D) They possess many different enzymes and they can reproduce independently of living cells but only at a slow rate

E) B) and C)
F) A) and D)

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Available evidence is consistent with the proposal that prion diseases are caused by infectious proteins.

A) True
B) False

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Viruses that are polyhedrons with 20 sides are said to have __________ symmetry.

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In which of the following stages of the viral infectious cycle do enveloped viruses usually acquire their envelopes?


A) penetration
B) component biosynthesis
C) assembly
D) release

E) B) and C)
F) A) and C)

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A __________ genome exists as several separate, nonidentical molecules that may be packaged together or separately.


A) diploid
B) segmented
C) polyploid
D) fractionated

E) All of the above
F) None of the above

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The presence or absence of an envelope is not useful in classifying viruses because any given virus may at one time have an envelope and at another time not have an envelope.

A) True
B) False

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Which of the following can be used to cultivate plant viruses?


A) cultures of separated plant cells
B) whole plants
C) plant protoplast cultures
D) All of these can be used to cultivate plant viruses.

E) A) and B)
F) C) and D)

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Bacterial viruses are so named because they have prokaryotic cell structures similar to their bacterial hosts.

A) True
B) False

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Which of the following is/are not true about viral envelopes?


A) The envelope proteins are virus specific.
B) The envelope lipids and carbohydrates are derived from the host.
C) They are typical lipid monolayers with embedded viral proteins.
D) The envelope proteins are virus specific and the envelope lipids and carbohydrates are derived from the host

E) C) and D)
F) A) and B)

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Viruses in the extracellular state possess few, if any, active enzymes.

A) True
B) False

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The mechanism of pathogenesis by prions may involve a conformational change in the prion protein (PrP) to an abnormal form.

A) True
B) False

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Viral envelopes are composed of


A) proteins.
B) lipids.
C) carbohydrates.
D) all of the choices

E) A) and B)
F) All of the above

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A ________ assay is most useful for determining the viability of a viral preparation?


A) direct (electron microscopic) count
B) hemagglutination
C) plaque
D) PCR

E) C) and D)
F) A) and B)

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Glycoprotein spikes protruding from the outer surface of viral envelopes function as


A) toxins.
B) factors that bind to host cells.
C) cell lysis factors.
D) factors needed for site specific recombination.

E) A) and D)
F) None of the above

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Many of the enzymes found in virus particles are


A) required for viral attachment to host cells.
B) involved in viral entry into host cells.
C) involved in the replication of viral nucleic acid.
D) all of the choices

E) A) and D)
F) All of the above

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Animal viruses have been cultivated in


A) suitable host animals.
B) embryonated eggs.
C) tissue cultures (monolayers of animal cells) .
D) all of the choices

E) A) and C)
F) B) and C)

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Viral capsid protein subunits are called


A) auxomers.
B) elastomers.
C) protomers.
D) viromers.

E) A) and B)
F) C) and D)

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Human cancer causing viruses most often have a ___________ genome.


A) ssDNA
B) dsDNA
C) ssRNA
D) dsRNA

E) All of the above
F) B) and D)

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Genes whose expression (or abnormal expression) causes cancer are called


A) cancer genes.
B) progenies.
C) oncogenes.
D) carcinogens.

E) A) and D)
F) A) and C)

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